The red fruit Buamella (scientific name: Pandanus conoideus, Japan scientific name: none, proposed Japan scientific name: Akaita konoki) is a rare plant of the family Octopus. Buamera grows naturally only on the island of Papua in Indonesia, and indigenous peoples have been consuming buamera as a nutrient-functional food for 30,000 years and have survived in a terrible environment. Dr. Toshiaki Nishigaki, who introduced noni to Japan in 2000, was looking for natural plants in Indonesia that contained carotenoids, which are lacking in noni. In 2005, Dr. Nishigaki encountered Buamera at a height of 1,500 meters on Papua Island, Indonesia, and immediately began joint research with the Faculty of Pharmaceutical Sciences, Nagasaki University, and discovered the world's first micronutrient beta cryptoxanthin. We have succeeded in soft-encapsulating the oil of the red fruit Buamella for the first time in the world. In 2007, based on the United Nations Convention on Biological Diversity, we signed a Material Transfer Agreement (MTA) with the Indonesian government and completed the introduction of the MTA to Japan. Obtained a Japan patent for the manufacture of buamera oil. We are conducting research with university research institutes in Japan and Indonesia on component analysis, safety research, absorption kinetics in humans, prevention of lung cancer and stomach cancer, improvement and prevention of postmenopausal osteoporosis, hair growth effect, acne improvement and healing effect, and whitening (melanin production suppression) effect. The results of these important research areas are reported at academic conferences and published in specialized journals. In 2017, the Indonesian government recognized the product as an innovative nutritional functional food of medicinal plants native to Indonesia for the first time at the IID2017 Development Exhibition held in the Netherlands (IID2017). In 2018, at the invitation of the International Chemical Society, he gave an invited lecture on the profile of buamera at the Chemical Society of Indonesia, and widely raised awareness of the importance of buamera for health. Beta cryptoxanthin is an essential micronutrient in the carotenoid system, and its deficiency is a health problem for Japan. Beta-cryptoxanthin, a natural health food without additives that is beneficial for feeding babies through breast milk, preventing and improving smoking, beauty, and age-related changes. Buamera 500VE contains 120 soft capsules and 500 mg per capsule, and it is believed that the concentration of beta cryptoxanthin in the blood can be maintained by taking 4 capsules a day with water. The total carotenoid content is more than 6 mg, and vitamin E is 16.4 mg. Naturally derived vitamin E is claimed as a nutrient functional food with a ratio of 260% of the nutrient dose contained in the daily intake to the standard value of nutrient labeling.